by michaelhalassa | Sep 14, 2025 | ADHD medication and psychosis, Algorithmic psychiatry, Chronic stimulant use, Computational psychiatry, Distributed neural systems, Dopamine and psychosis, Healthcare, Mental health treatment, Michael Halassa, Predictive systems, Psychiatry, Reward-seeking systems, Stimulant side effects, Stimulant-induced psychosis
The Portal in the Basement The EMTs who brought Stephanie to the inpatient unit looked genuinely unsettled. She’d been found at 3 AM, methodically photographing her neighbors’ houses with her phone, documenting what she described as “dimensional...
by michaelhalassa | Jul 16, 2025 | Cobenfy, Algorithmic psychiatry, Computational psychiatry, Distributed neural systems, Dopamine and psychosis, KarXT, Mental health treatment, Michael Halassa, muscarinic antipsychotic, Schizophrenia treatment, Xanomeline
I had the privilege of attending and in part organizing the inaugural Innovation in Psychosis Therapeutics Summit in Boston (June 9-11, 2025). This intimate gathering brought together scientists, clinicians and biotech leaders who share a common goal: to finally push...
by michaelhalassa | Jul 11, 2025 | Algorithmic psychiatry, Healthcare, Mental health treatment, muscarinic antipsychotic, Schizophrenia treatment
The recent Innovation in Psychosis Therapeutics Summit in Boston revealed a clear truth: while the field celebrates breakthroughs like muscarinic agents, it’s equally clear that psychiatric drug development needs a neuroscience reboot. We’ve mastered...
by | May 6, 2025 | Algorithmic psychiatry, Computational psychiatry, Mental health treatment, Schizophrenia treatment-resistant
Why Mental Health Treatments Need Algorithmic “Flight Simulators” I would like to highlight a recent perspective article that my colleagues and I have recently published: https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00167-3 Despite...