by michaelhalassa | Sep 14, 2025 | ADHD medication and psychosis, Algorithmic psychiatry, Chronic stimulant use, Computational psychiatry, Distributed neural systems, Dopamine and psychosis, Healthcare, Mental health treatment, Michael Halassa, Predictive systems, Psychiatry, Reward-seeking systems, Stimulant side effects, Stimulant-induced psychosis
The Portal in the Basement The EMTs who brought Stephanie to the inpatient unit looked genuinely unsettled. She’d been found at 3 AM, methodically photographing her neighbors’ houses with her phone, documenting what she described as “dimensional...
by michaelhalassa | Jul 16, 2025 | Cobenfy, Algorithmic psychiatry, Computational psychiatry, Distributed neural systems, Dopamine and psychosis, KarXT, Mental health treatment, Michael Halassa, muscarinic antipsychotic, Schizophrenia treatment, Xanomeline
I had the privilege of attending and in part organizing the inaugural Innovation in Psychosis Therapeutics Summit in Boston (June 9-11, 2025). This intimate gathering brought together scientists, clinicians and biotech leaders who share a common goal: to finally push...
by michaelhalassa | Jul 10, 2025 | Computational psychiatry, Executive Control, Michael Halassa, Reinforcement learning, Schizophrenia
As a psychiatrist who treats patients with schizophrenia, I’ve long been struck by a fundamental puzzle: why do individuals with psychosis hold onto beliefs with such unwavering certainty, even when presented with compelling contradictory evidence? The answer,...
by | Sep 12, 2024 | Healthcare, Michael Halassa, Psychiatry
Mental health care has long been dominated by the Diagnostic and Statistical Manual of Mental Disorders (DSM), a classification system that guides clinicians in diagnosing and treating psychiatric illnesses. While the DSM has provided a standardized approach to...
